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Yan Q Xiong Selected Research

Endocarditis

12/2021New Mechanistic Insights into Purine Biosynthesis with Second Messenger c-di-AMP in Relation to Biofilm-Related Persistent Methicillin-Resistant Staphylococcus aureus Infections.
12/2021Proteoglycan 4 (lubricin) is a highly sialylated glycoprotein associated with cardiac valve damage in animal models of infective endocarditis.
1/2021Efficacy of Antistaphylococcal Lysin LSVT-1701 in Combination with Daptomycin in Experimental Left-Sided Infective Endocarditis Due to Methicillin-Resistant Staphylococcus aureus.
1/2020Globally deimmunized lysostaphin evades human immune surveillance and enables highly efficacious repeat dosing.
1/2020Ability of Bicarbonate Supplementation To Sensitize Selected Methicillin-Resistant Staphylococcus aureus Strains to β-Lactam Antibiotics in an Ex Vivo Simulated Endocardial Vegetation Model.
1/2020Effect of the Lysin Exebacase on Cardiac Vegetation Progression in a Rabbit Model of Methicillin-Resistant Staphylococcus aureus Endocarditis as Determined by Echocardiography.
1/2019The Antistaphylococcal Lysin, CF-301, Activates Key Host Factors in Human Blood To Potentiate Methicillin-Resistant Staphylococcus aureus Bacteriolysis.
10/2017A Human Biofilm-Disrupting Monoclonal Antibody Potentiates Antibiotic Efficacy in Rodent Models of both Staphylococcus aureus and Acinetobacter baumannii Infections.
1/2017Telavancin Is Active against Experimental Aortic Valve Endocarditis Caused by Daptomycin- and Methicillin-Resistant Staphylococcus aureus Strains.
11/2016The Global Regulon sarA Regulates β-Lactam Antibiotic Resistance in Methicillin-Resistant Staphylococcus aureus In Vitro and in Endovascular Infections.
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Yan Q Xiong Research Topics

Disease

35Infections
12/2021 - 01/2008
33Endocarditis
12/2021 - 01/2005
11Bacteremia
01/2020 - 01/2010
4Autolysis
12/2021 - 01/2008
2Bacterial Infections (Bacterial Infection)
01/2021 - 10/2017
2Staphylococcal Infections
01/2019 - 01/2008
2Abscess
11/2015 - 12/2014
1Persistent Infection
12/2021
1Cardiovascular Infections
01/2021
1Pneumonia (Pneumonitis)
01/2018
1Drug-Related Side Effects and Adverse Reactions
01/2017
1Body Weight (Weight, Body)
07/2015
1Sepsis (Septicemia)
03/2013

Drug/Important Bio-Agent (IBA)

16Anti-Bacterial Agents (Antibiotics)IBA
12/2021 - 01/2005
12VancomycinFDA LinkGeneric
12/2021 - 01/2009
11DaptomycinFDA Link
01/2021 - 01/2008
5LactamsIBA
01/2020 - 11/2016
4Oxacillin (Prostaphlin)FDA LinkGeneric
11/2019 - 01/2009
4Linezolid (Zyvox)FDA Link
01/2019 - 06/2012
4Antimicrobial Cationic PeptidesIBA
10/2015 - 01/2008
3purineIBA
12/2021 - 01/2018
3Biomarkers (Surrogate Marker)IBA
12/2021 - 10/2011
3Pharmaceutical PreparationsIBA
01/2021 - 01/2008
3Serine (L-Serine)FDA Link
05/2019 - 10/2008
3Staphylococcus aureus RNAIIIIBA
01/2019 - 12/2011
3telavancinFDA Link
01/2017 - 11/2012
3Fibronectins (Fibronectin)IBA
12/2015 - 11/2009
3Virulence Factors (Pathogenicity Factors)IBA
12/2013 - 10/2011
2EnzymesIBA
12/2021 - 01/2020
2Glycoproteins (Glycoprotein)IBA
12/2021 - 12/2014
2exebacaseIBA
01/2020 - 01/2019
2Rifampin (Rifampicin)FDA LinkGeneric
01/2019 - 01/2018
2bacterial fibronectin-binding proteinsIBA
12/2015 - 11/2009
2Interleukin-22 (IL-22)IBA
11/2015 - 12/2014
2Interleukin-17 (Interleukin 17)IBA
11/2015 - 12/2014
2human neutrophil peptide 1IBA
10/2015 - 01/2008
2Membrane Glycoproteins (Membrane Glycoprotein)IBA
01/2013 - 10/2008
2Fibrinogen (Factor I)FDA Link
01/2013 - 08/2010
2Proteins (Proteins, Gene)FDA Link
01/2010 - 01/2008
2ThrombinFDA Link
01/2010 - 01/2008
1AcidsIBA
12/2021
1Adenosine Diphosphate (ADP)IBA
12/2021
1Adenosine Triphosphate (ATP)IBA
12/2021
1cyclic diadenosine phosphateIBA
12/2021
1DNA (Deoxyribonucleic Acid)IBA
12/2021
1lubricinIBA
12/2021
1Proteoglycans (Proteoglycan)IBA
12/2021
1Peptides (Polypeptides)IBA
01/2021
1LysostaphinIBA
01/2020
1hypericinIBA
11/2019
1Proline (L-Proline)FDA Link
08/2019
1Fenofibrate (CiL)FDA LinkGeneric
08/2019
1Imipenem Drug Combination Cilastatin (Primaxin)FDA Link
08/2019
1Antimicrobial PeptidesIBA
08/2019
1TRL1068IBA
10/2017
1Monoclonal AntibodiesIBA
10/2017
1Penicillin-Binding Proteins (Penicillin-Binding Protein)IBA
11/2016
15'-N-methylcarboxamideadenosineIBA
11/2016
1tedizolid phosphateIBA
01/2016
1Methicillin (Metin)FDA Link
01/2016
1tedizolidIBA
01/2016
1tiamulinIBA
01/2016
1LigandsIBA
12/2015
1Carrier Proteins (Binding Protein)IBA
12/2015
1Interferon-gamma (Interferon, gamma)IBA
11/2015
1Neutralizing AntibodiesIBA
11/2015
1valnemulinIBA
07/2015
1phenyl-2-aminoethyl sulfide (PAES)IBA
01/2015
1cefquinomeIBA
01/2015
1VaccinesIBA
12/2014
1AntigensIBA
12/2014
1Peptide Hydrolases (Proteases)FDA Link
04/2014
1Capsules (Microcapsules)IBA
12/2013
1Anti-Infective Agents (Microbicides)IBA
06/2012
1Interleukin-8 (Interleukin 8)IBA
01/2012
1plectasinIBA
11/2011
1alpha,beta-diacryloxypropionic acid (DAPS)IBA
08/2010
1Staphylococcus aureus delta hemolysin proteinIBA
01/2010
1Glutamine (L-Glutamine)FDA Link
10/2009
1Biocompatible Materials (Biomaterials)IBA
10/2009
1glutamine permeaseIBA
10/2009
1HydrolasesIBA
01/2009
1Peptidoglycan (Murein)IBA
01/2009
1Etorphine (M99)IBA
10/2008
1Phospholipids (Phosphatides)FDA LinkGeneric
01/2008

Therapy/Procedure

13Therapeutics
01/2021 - 01/2009
5Catheters
10/2017 - 10/2009
1Phage Therapy
06/2020